Jian-Zhi Wang Selected Research

Memory Disorders (Memory Loss)

1/2021	Platelet biomarkers for a descending cognitive function: A proteomic approach.
1/2021	STAT3 ameliorates cognitive deficits via regulation of NMDAR expression in an Alzheimer's disease animal model.
1/2020	Co-Expression of Three Wild-Type 3R-Tau Isoforms Induces Memory Deficit via Oxidation-Related DNA Damage and Cell Death: A Promising Model for Tauopathies.
1/2020	Tau inhibits PKA by nuclear proteasome-dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation.
8/2019	Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting.
4/2019	Folate/Vitamin B Alleviates Hyperhomocysteinemia-Induced Alzheimer-Like Pathologies in Rat Retina.
1/2019	Tau accumulation triggers STAT1-dependent memory deficits by suppressing NMDA receptor expression.
1/2019	Elevation of pS262-Tau and Demethylated PP2A in Retina Occurs Earlier than in Hippocampus During Hyperhomocysteinemia.
1/2018	Inhibition of Histone Acetylation by ANP32A Induces Memory Deficits.
1/2018	A Novel MicroRNA-124/PTPN1 Signal Pathway Mediates Synaptic and Memory Deficits in Alzheimer's Disease.

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Jian-Zhi Wang Research Topics

Disease

114	Alzheimer Disease (Alzheimer's Disease) 04/2022 - 03/2002
38	Memory Disorders (Memory Loss) 01/2021 - 06/2007
30	Cognitive Dysfunction 04/2022 - 11/2009
22	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 03/2002
20	Tauopathies 01/2022 - 08/2002
13	Hyperhomocysteinemia 01/2020 - 04/2009
10	Amyloid Plaque 01/2022 - 09/2012
9	Neuroblastoma 01/2015 - 04/2004
7	Dementia (Dementias) 01/2022 - 11/2007
3	Neuroinflammatory Diseases 12/2020 - 01/2016
3	Schizophrenia (Dementia Praecox) 01/2020 - 06/2011
3	Inflammation (Inflammations) 01/2019 - 07/2013
2	Type 2 Diabetes Mellitus (MODY) 10/2021 - 01/2021
2	Mitochondrial Diseases (Mitochondrial Disease) 12/2020 - 06/2018
2	Mental Disorders (Mental Disorder) 01/2020 - 01/2017
2	Neoplasms (Cancer) 01/2019 - 10/2015
2	Infections 01/2019 - 01/2014
2	Hypertension (High Blood Pressure) 11/2017 - 03/2016
2	Insulin Resistance 04/2014 - 01/2014
2	Wounds and Injuries (Trauma) 04/2014 - 07/2009
2	Brain Ischemia (Cerebral Ischemia) 10/2010 - 07/2009
2	Hypoxia (Hypoxemia) 08/2007 - 09/2005
1	Obesity 01/2022
1	Nervous System Diseases (Neurological Disorders) 01/2021
1	Seizures (Absence Seizure) 01/2020

Drug/Important Bio-Agent (IBA)

34	Proteins (Proteins, Gene)FDA Link 10/2021 - 03/2002
29	Amyloid (Amyloid Fibrils)IBA 01/2022 - 08/2006
13	Glycogen Synthase (Synthase I)IBA 04/2022 - 01/2007
13	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2020 - 08/2004
13	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2020 - 09/2004
9	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2009
9	asparaginylendopeptidase (legumain)IBA 01/2021 - 11/2014
9	MelatoninIBA 07/2013 - 02/2002
8	tau Proteins (tau Protein)IBA 01/2020 - 10/2009
7	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2021 - 04/2009
7	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2020 - 09/2004
7	HomocysteineIBA 08/2019 - 01/2011
6	Amyloid beta-PeptidesIBA 01/2022 - 08/2006
6	Cholinergic Agents (Cholinergics)IBA 01/2021 - 01/2013
6	Glycogen Synthase Kinase 3IBA 01/2013 - 05/2005
5	Phosphotransferases (Kinase)IBA 04/2022 - 08/2004
5	Pharmaceutical PreparationsIBA 01/2022 - 02/2013
5	Protein Kinases (Protein Kinase)IBA 01/2020 - 04/2004
4	Peptides (Polypeptides)IBA 04/2022 - 12/2014
4	Peptide Hydrolases (Proteases)FDA Link 01/2021 - 01/2009
4	Protein Isoforms (Isoforms)IBA 01/2020 - 06/2011
4	Histones (Histone)IBA 01/2020 - 01/2017
4	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020 - 10/2015
4	CytokinesIBA 01/2019 - 07/2009
4	Synapsins (Synapsin I)IBA 11/2018 - 01/2012
4	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 12/2015 - 08/2004
4	Scopolamine (Hyoscine)FDA Link 10/2015 - 01/2013
4	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 03/2013 - 04/2003
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2021 - 01/2012
3	Folic Acid (Vitamin M)FDA LinkGeneric 04/2019 - 04/2009
3	ZincIBA 01/2018 - 03/2012
3	Neuroprotective AgentsIBA 01/2018 - 11/2017
3	Estrogens (Estrogen)FDA Link 03/2016 - 06/2008
3	SynaptophysinIBA 01/2015 - 01/2012
3	Acetylcarnitine (Alcar)IBA 01/2014 - 09/2011
3	WortmanninIBA 09/2008 - 02/2002
3	Neurofilament ProteinsIBA 06/2008 - 03/2002
3	calyculin AIBA 08/2007 - 04/2004
3	Protein Subunits (Protein Subunit)IBA 02/2007 - 08/2002
2	Transcription Factors (Transcription Factor)IBA 10/2021 - 01/2018
2	Apolipoproteins E (ApoE)IBA 10/2021 - 03/2016
2	Messenger RNA (mRNA)IBA 01/2020 - 06/2008
2	SaltsIBA 01/2020 - 11/2017
2	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 04/2019 - 01/2011
2	Insulin (Novolin)FDA Link 01/2019 - 03/2016
2	Sirtuin 1IBA 06/2018 - 04/2014
2	SynucleinsIBA 01/2018 - 08/2017
2	Fluoxetine (Prozac)FDA LinkGeneric 11/2017 - 01/2017
2	JNK Mitogen-Activated Protein KinasesIBA 12/2015 - 10/2010
2	Small Interfering RNA (siRNA)IBA 12/2015 - 12/2013
2	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 02/2015 - 01/2007
2	Streptozocin (Streptozotocin)FDA Link 01/2015 - 04/2014
2	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2009 - 04/2007
2	Acetylcholine (Acetylcholine Chloride)FDA Link 09/2008 - 05/2008
2	bisindolylmaleimide IIBA 09/2008 - 05/2005
2	Cytoskeletal ProteinsIBA 08/2007 - 04/2004
2	Peroxynitrous Acid (Peroxynitrite)IBA 07/2006 - 04/2005
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2022
1	Amino Acids FDA Link 01/2022
1	Erythropoietin FDA Link 01/2022
1	EnzymesIBA 01/2022
1	Apolipoprotein E4IBA 10/2021
1	ApolipoproteinsIBA 10/2021
1	snake venom protein C activatorIBA 01/2021
1	AsparagineIBA 01/2021
1	Neurotransmitter Agents (Neurotransmitter)IBA 12/2020
1	AMP-Activated Protein KinasesIBA 08/2020
1	Glycogen Synthase Kinase 3 betaIBA 01/2020
1	SolutionsIBA 01/2020
1	Dizocilpine Maleate (Dizocilpine)IBA 01/2020
1	Neuregulin-1 (Neuregulin 1)IBA 01/2020
1	IonsIBA 01/2020

Therapy/Procedure

6	Therapeutics 01/2021 - 06/2013
3	Intraperitoneal Injections 05/2014 - 01/2013
1	Drug Therapy (Chemotherapy) 12/2020